Morphology and function of Bast's valve: additional insight in its functioning using 3D-reconstruction

被引:27
作者
Hofman, R. [1 ]
Segenhout, J. M. [1 ]
Buytaert, J. A. N. [2 ]
Dirckx, J. J. J. [2 ]
Wit, H. P. [1 ]
机构
[1] Univ Groningen, Med Ctr, Dept Otorhinolaryngol, NL-9700 RB Groningen, Netherlands
[2] Univ Antwerp, Lab BioMed Phys, Dept Phys, B-2020 Antwerp, Belgium
关键词
Utriculo-endolymphatic valve; Bast's valve; OPFOS; imaging; endolymphatic system; 3D-reconstruction;
D O I
10.1007/s00405-007-0424-8
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 [耳鼻咽喉科学];
摘要
The utriculo-endolymphatic valve was discovered by Bast in 1928. The function of Bast's valve is still unclear. By means of orthogonal-plane fluorescence optical sectioning (OPFOS) microscopy 3D-reconstructions of the valve and its surrounding region are depicted. The shape of the duct at the utricular side is that of a flattened funnel. In the direction of the endolymphatic duct and sac this funnel runs into a very narrow duct. The valve itself has a rigid 'arch-like' configuration. The opposing thin, one cell-layer thick, utricular membrane is highly compliant. We propose that opening and closure of the valve occurs through movement of the flexible base/utricular membrane away from and toward the relatively rigid valve lip.
引用
收藏
页码:153 / 157
页数:5
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