A simple catalytic system for the substitutive carbonylation of allyl alcohols to beta,gamma-unsaturated acids or esters

被引：26

作者：

Gabriele, B

Salerno, G

Costa, M

Chiusoli, GP

机构：

[1] UNIV CALABRIA,DIPARTIMENTO CHIM,I-87030 ARCAVACATA,COSENZA,ITALY

[2] UNIV PARMA,DIPARTIMENTO CHIM ORGAN & IND,I-43100 PARMA,ITALY

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1996年 / 111卷 / 1-2期

关键词：

carbonylation; allyl alcohols; carboxylic acids; esters; palladium;

D O I：

10.1016/1381-1169(96)00122-7

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Allyl alcohols can be efficiently carbonylated to beta,gamma-unsaturated acids or esters in dimethylacetamide (DMA) or MeOH/DMA mixtures under relatively mild conditions (80 degrees C, 50-100 atm) using a simple catalytic system consisting of palladium iodide in the presence of thiourea as ligand. In the case of but-2-ene-1,4-diol, selectivation to methyl 5-hydroxypent-3-enoate, 3,6-dihydro-1,2-pyrone or dimethyl hex-3-enedioate may be achieved.

引用

页码：43 / 48

页数：6

共 37 条

[1] SYNTHESIS OF ETHYL (2RS,3SR)-1-TOSYL-3-VINYLAZETIDINE-2-CARBOXYLATE AND ETHYL (2RS,E)-3-ETHYLIDENE-1-TOSYLAZETIDINE-2-CARBOXYLATE (= RAC-ETHYL N-TOSYLPOLYOXIMATE) [J].