Communicative interaction of myosins along an actin filament in the presence of ATP

被引:23
作者
Hatori, K [1 ]
Honda, H [1 ]
Matsuno, K [1 ]
机构
[1] NAGAOKA UNIV TECHNOL,DEPT BIOENGN,NAGAOKA,NIIGATA 94021,JAPAN
关键词
actin; ATP; filamental fluctuations; myosin;
D O I
10.1016/0301-4622(96)00008-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Myosin molecules contacting an actin filament in the presence of ATP were found to regulate the filamental fluctuations due to ATP hydrolysis in a communicative manner alone the filament. As an evidence of the occurrence of the communication, ATP-activated fluctuating displacements of the filament in the direction perpendicular to its longitudinal axis were identified to propagate at a finite velocity not less than about 0.2 mu m/s unidirectionally along the filament.
引用
收藏
页码:149 / 152
页数:4
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