Oral ketoprofen is effective in the treatment of non-infectious lameness in sows

被引:32
作者
Mustonen, Katja [1 ]
Ala-Kurikka, Eve [2 ]
Orro, Toomas [3 ]
Peltoniemi, Olli [2 ]
Raekallio, Marja [1 ]
Vainio, Outi [1 ]
Heinonen, Mari [2 ]
机构
[1] Univ Helsinki, Dept Equine & Small Anim Med, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Dept Prod Anim Med, Saarentaus 04920, Finland
[3] Estonian Univ Life Sci, Dept Anim Hlth & Environm, EE-51014 Tartu, Estonia
基金
芬兰科学院;
关键词
Pig; Locomotor disorders; Orthopaedic treatment; Non-steroidal anti-inflammatory drugs; Efficacy; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; SERUM-HAPTOGLOBIN; DISORDERS; GILTS; PIGS; PHENYLBUTAZONE; EFFICACY; PAIN;
D O I
10.1016/j.tvjl.2010.09.017
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The efficacy of ketoprofen in the treatment of non-infectious lameness in sows was examined in a double-blinded study. Two dose rates of oral ketoprofen were compared to placebo treatment over five consecutive days. Lameness was assessed with a five-grade scoring system prior to and on the last day of the treatment. The rate of treatment success was 54.3% for the ketoprofen 4 mg/kg group (n = 46), 53.2% for the ketoprofen 2 mg/kg group (n = 47) and 20.8% for the pigs in the placebo group (is = 48). The difference between both ketoprofen groups and the placebo group was significant (P = 0.001), but there was no difference between the two ketoprofen groups (P = 0.78). Oral ketoprofen was well tolerated and no adverse events were observed. As lameness is a very common problem in sows, oral ketoprofen appeared to be a practical way to alleviate pain and improve the welfare of sows. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:55 / 59
页数:5
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