A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester

被引：24

作者：

Cossy, J

Mirguet, O

Pardo, DG

Desmurs, JR

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, Chim Organ Lab, F-75231 Paris 05, France

[2] Rhodia, F-69457 Lyon 06, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(01)01666-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A diastereoselective conjugate addition of an organocopper reagent to a chiral racemic olefinic amido ester has been used as the key step in a formal total synthesis of paroxetine. (C), 2001 Published by Elsevier Science Ltd.

引用

页码：7805 / 7807

页数：3

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