Healing of Euchromatic Chromosome Breaks by Efficient de novo Telomere Addition in Drosophila melanogaster

被引：19

作者：

Titen, Simon W. A. ^{[1
]}

Golic, Kent G. ^{[1
]}

机构：

[1] Univ Utah, Dept Biol, Salt Lake City, UT 84112 USA

来源：

GENETICS | 2010年 / 184卷 / 01期

基金：

美国国家卫生研究院;

关键词：

P-ELEMENTS; TRANSPOSITION; APOPTOSIS; MUTATOR;

D O I：

10.1534/genetics.109.109934

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Previously, we observed that heterochromatic 4 and Y chromosomes that had experienced breakage in the male germline were frequently transmitted to progeny. Their behavior suggested that they carried functional telomeres. Here we show that efficient healing by de novo telomere addition is not unique to heterochromatic breaks.

引用

页码：309 / 312

页数：4

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