Nematicidal alkaloids and related compounds produced by the fungus Penicillium cf. simplicissimum

被引：70

作者：

Kusano, M

Koshino, H

Uzawa, J

Fujioka, S

Kawano, T

Kimura, Y ^{[1
]}

机构：

[1] Tottori Univ, Fac Agr, Dept Agr Chem, Tottori 6808553, Japan

[2] Inst Phys & Chem Res, Wako, Saitama 3510198, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 12期

关键词：

Penicillium cf. simplicissimum; peniprequinolone; dihydroquinolinones; nematicidal activity;

D O I：

10.1271/bbb.64.2559

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new nematicidal alkaloid, peniprequinolone (1), together with the known alkaloids penigequinolones A and B (2a,2b), 3-methoxy-4-hydroxy-4-(4'-methoxyphenyl)quinolinone (3), and 3-methoxy-4,6-dihydroxy-4-(4'-methoxyphenyl)quinolinone (4), were isolated from Penicillium cf. simplicissimum (Oudemans) Them. Cyclopenin (5) and a compound (6a/6b) structurally related to cyclopenin also were isolated from the fungus, and their structures were established by spectroscopic analysis. The biological activities of 1, 2, 3, 4, and 5 were examined by a bioassay with root-lesion nematodes.

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页码：2559 / 2568

页数：10

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