共 74 条
Facile DNA Immobilization on Surfaces through a Catecholamine Polymer
被引:230
作者:

Ham, Hyun Ok
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机构:
Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA

Liu, Zhongqiang
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机构:
Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA

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Lee, Haeshin
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机构:
Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea
Korea Adv Inst Sci & Technol, Grad Sch Nanosci & Technol WCU, Taejon 305701, South Korea Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA

Messersmith, Phillip B.
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h-index: 0
机构:
Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
Northwestern Univ, Dept Mat Sci & Engn, Chem & Biol Engn Dept, Chem Life Proc Inst,Inst Bionanotechnol Med, Evanston, IL 60208 USA
Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
机构:
[1] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
[2] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea
[3] Korea Adv Inst Sci & Technol, Grad Sch Nanosci & Technol WCU, Taejon 305701, South Korea
[4] Northwestern Univ, Dept Mat Sci & Engn, Chem & Biol Engn Dept, Chem Life Proc Inst,Inst Bionanotechnol Med, Evanston, IL 60208 USA
[5] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA
基金:
新加坡国家研究基金会;
关键词:
biomimetic synthesis;
biosensors;
catecholamine;
DNA immobilization;
surface modification;
COVALENT ATTACHMENT;
TOF-SIMS;
MICROARRAY;
OLIGONUCLEOTIDES;
FLUORESCENCE;
STRATEGIES;
GOLD;
XPS;
IDENTIFICATION;
FABRICATION;
D O I:
10.1002/anie.201005001
中图分类号:
O6 [化学];
学科分类号:
070301 [无机化学];
摘要:
Simple immersion of noble metals, oxides, semiconductors, and synthetic polymer substrates in a mussel-mimetic catecholamine polymer solution p(DOMA-AEMA) leads to formation of a thin film on the substrate. The resulting coated substrates can bind DNA without further surface treatment. This approach provides a new entrance to DNA microarray fabrication. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码:732 / 736
页数:5
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