Heterocyclic analogues of carbazole alkaloids

被引：90

作者：

Kirsch, GH ^{[1
]}

机构：

[1] Univ Metz, Fac Sci, Lab Ingn Mol & Biochim Pharmacol, F-57000 Metz, France

来源：

CURRENT ORGANIC CHEMISTRY | 2001年 / 5卷 / 05期

关键词：

D O I：

10.2174/1385272013375409

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carbazole containing alkaloids (e.g. ellipticine and related compounds, indolocarbazoles......) have caught the attention of the chemists and biochemists due to their biological activities (antitumor, antiviral, protein kinase inhibitors......). Numerous total syntheses of the natural compounds have been effected as well as structural modifications for annulating various heterocyclic systems to the carbazole. Interest in these modifications lays in the possible changes in biological activities. This review will present some of the aspects of the chemistry developped recently to introduce such modifications.

引用

页码：507 / 518

页数：12

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