Analytical and bioanalytical applications of carbon dots

被引:571
作者
Esteves da Silva, Joaquim C. G. [1 ]
Goncalves, Helena M. R. [1 ]
机构
[1] Univ Porto, Fac Sci, Dept Chem & Biochem, CIQ UP, P-4169007 Oporto, Portugal
关键词
Analytical application; Bioanalysis; Bioimaging; Carbon-based nanoparticle; Carbon dot; Fluorescence; Functionalization; Luminescence; Passivation; Synthesis; SILICON NANOCRYSTALS; OPTICAL-PROPERTIES; NANOPARTICLES; FLUORESCENCE; LUMINESCENCE; NANOTUBES; GRAPHENE;
D O I
10.1016/j.trac.2011.04.009
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Carbon dots (CDs) comprise a recently discovered class of strongly fluorescent, emission-color-tuning and non-blinking nanoparticles with great analytical and bioanalytical potential. Raw CDs can be obtained by laser ablation or electrochemical exfoliation of graphite, from soot, or thermal carbonization, acid dehydration or ultrasonic treatment of molecular precursors. Passivation of raw CDs makes them fluorescent and their functionalization confers reactivity towards selected targets. CDs can be excited by single-photon (ultraviolet or near-ultraviolet) and multi-photon (red or near-infrared) excitation, and their luminescence properties are due to surface defects. CDs are being proposed as bioimaging probes because they comprise non-toxic elements and are biocompatible. Passivated and functionalized CDs can be made to sense pH, metal ions and molecular substances. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1327 / 1336
页数:10
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