Conicamin, a novel histamine antagonist from the Mediterranean tunicate Aplidium conicum

被引：22

作者：

Aiello, A

Borrelli, F

Capasso, R

Fattorusso, E

Luciano, P

Menna, M

机构：

[1] Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy

[2] Dipartimento Farmacol Sperimentale, I-80131 Naples, Italy

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 24期

关键词：

D O I：

10.1016/j.bmcl.2003.08.081

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In addition to the known 6-bromo-hypaphorine (2) and plakohypaphorine-A (3), the methanol extract of the Mediterranean tunicate Aplidium conicum was shown to contain conicamin, a novel indole alkaloid having histamine-antagonistic activity which structure was determined to be 1 on the basis of the spectral data. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：4481 / 4483

页数：3

共 20 条

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