Liver Neoplasia in Children

被引:43
作者
Hadzic, Nedim [1 ]
Finegold, Milton J. [2 ]
机构
[1] Kings Coll Hosp London, Paediat Liver Serv, London SE5 9RS, England
[2] Texas Childrens Hosp, Baylor Coll Med, Houston, TX 77030 USA
关键词
Liver neoplasia; Pediatric liver tumors; Hepatocellular carcinoma; Hepatoblastoma; BECKWITH-WIEDEMANN-SYNDROME; STROMAL-EPITHELIAL TUMOR; PEDIATRIC-ONCOLOGY-GROUP; HEPATOCELLULAR-CARCINOMA; INFANTILE HEMANGIOMAS; INTERNATIONAL-SOCIETY; HEPATIC MALIGNANCY; SURGICAL RESECTION; POOR-PROGNOSIS; BETA-CATENIN;
D O I
10.1016/j.cld.2011.03.011
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Management of pediatric liver tumors has significantly improved over the last 2 decades. The management options for hepatocelluar carcinoma (HOC) are not well defined. In the pediatric context, the main clinical aims are to reduce chemotherapy toxicity (predominantly ototoxicity and nephrotoxicity) in children treated for hepatoblastoma and to investigate additional modes of treatment for HOC. An increasing number of children develop HOC in the background of chronic liver disease, and screening methods need to be better observed.
引用
收藏
页码:443 / +
页数:21
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