Murine natural killer cell activation receptors

被引:31
作者
Smith, HRC
Idris, AH
Yokoyama, WM [1 ]
机构
[1] Washington Univ, Sch Med, Howard Hughes Med Inst, Div Rheumatol,Dept Med, St Louis, MO 63110 USA
[2] Mt Sinai Sch Med, Immunobiol Ctr, New York, NY USA
关键词
D O I
10.1034/j.1600-065X.2001.1810109.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK-cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.
引用
收藏
页码:115 / 125
页数:11
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