Association of childhood acute lymphoblastic leukaemia with cancers in family members

被引:16
作者
Couto, E [1 ]
Chen, B
Hemminki, K
机构
[1] Karolinska Inst, Novum, Dept Biosci, S-14157 Huddinge, Sweden
[2] DKFZ, German Canc Res Ctr, Div Mol Genet Epidemiol, Heidelberg, Germany
关键词
childhood acute lymphoblastic leukaemia; family history; prenatal origin; testicular cancer;
D O I
10.1038/sj.bjc.6602867
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Children whose twins have had leukaemia have a higher risk of contracting acute lymphoblastic leukaemia (ALL), confirming a prenatal origin of the disease. This association was not true when considering other types of affected first-degree relatives. Children whose fathers were diagnosed with testicular cancer have a higher risk of ALL.
引用
收藏
页码:1307 / 1309
页数:3
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