Muscle development: Electrical control of gene expression

被引:37
作者
Hughes, SM
机构
[1] Univ London Kings Coll, MRC, Muscle & Cell Motil Unit, Randall Inst, London WC2B 5RL, England
[2] Univ London Kings Coll, Dev Biol Res Ctr, Randall Inst, London WC2B 5RL, England
关键词
D O I
10.1016/S0960-9822(07)00554-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The electrical activity resulting from stimulation by motor neurons regulates gene expression in skeletal muscle fibres, A recent study has suggested a mechanism by which distinct patterns of electrical stimulus might be integrated to control the contractile properties of these fibres.
引用
收藏
页码:R892 / R894
页数:3
相关论文
共 11 条
[1]   Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells [J].
Abbott, KL ;
Friday, BB ;
Thaloor, D ;
Murphy, TJ ;
Pavlath, GK .
MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (10) :2905-2916
[2]   The AM and FM of calcium signalling [J].
Berridge, MJ .
NATURE, 1997, 386 (6627) :759-760
[3]  
CALVO S, 1998, IN PRESS MOL CELL BI, V9
[4]   A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type [J].
Chin, ER ;
Olson, EN ;
Richardson, JA ;
Yano, Q ;
Humphries, C ;
Shelton, JM ;
Wu, H ;
Zhu, WG ;
Bassel-Duby, R ;
Williams, RS .
GENES & DEVELOPMENT, 1998, 12 (16) :2499-2509
[5]   Both myoblast lineage and innervation determine fiber type and are required for expression of the slow myosin heavy chain 2 gene [J].
DiMario, JX ;
Stockdale, FE .
DEVELOPMENTAL BIOLOGY, 1997, 188 (01) :167-180
[6]  
Dirix A, 1988, OLYMPIC BOOK SPORTS
[7]   Differential activation of transcription factors induced by Ca2+ response amplitude and duration [J].
Dolmetsch, RE ;
Lewis, RS ;
Goodnow, CC ;
Healy, JI .
NATURE, 1997, 386 (6627) :855-858
[8]   ISOLATION OF 2 NEW MEMBERS OF THE NF-AT GENE FAMILY AND FUNCTIONAL-CHARACTERIZATION OF THE NF-AT PROTEINS [J].
HOEY, T ;
SUN, YL ;
WILLIAMSON, K ;
XU, X .
IMMUNITY, 1995, 2 (05) :461-472
[9]   MyoD protein is differentially accumulated in fast and slow skeletal muscle fibres and required for normal fibre type balance in rodents [J].
Hughes, SM ;
Koishi, K ;
Rudnicki, M ;
Maggs, AM .
MECHANISMS OF DEVELOPMENT, 1997, 61 (1-2) :151-163
[10]   EFFECTS OF CYCLOSPORINE-A ON SKELETAL-MUSCLE MITOCHONDRIAL RESPIRATION AND ENDURANCE TIME IN RATS [J].
MERCIER, JG ;
HOKANSON, JF ;
BROOKS, GA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 151 (05) :1532-1536