Identification of a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2 metallo-β-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae

被引：80

作者：

Yan, JJ

Ko, WC

Wu, JJ

机构：

[1] Natl Cheng Kung Univ, Dept Med Technnol, Coll Med, Tainan 70101, Taiwan

[2] Natl Cheng Kung Univ, Med Ctr, Dept Pathol, Tainan 70101, Taiwan

[3] Natl Cheng Kung Univ, Med Ctr, Dept Med, Tainan 70101, Taiwan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 08期

关键词：

D O I：

10.1128/AAC.45.8.2368-2371.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A multidrug-resistant plasmid encoding TEM-1, SHV-12, and a variant of IMP-2 metallo-beta -lactamase, designated IMP-8, was identified from a clinical isolate of Klebsiella pneumoniae. There are four nucleotide differences between bla(IMP-2) and bla(IMP-8), resulting in two amino acid differences. bla(IMP-8) was also found to be carried by an integron-borne gene cassette similar to the bla(IMP-2) cassette.

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页码：2368 / 2371

页数：4

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