A new general synthesis of isomeric nucleosides

被引：19

作者：

Bera, S ^{[1
]}

Nair, V ^{[1
]}

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 34期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(01)01118-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient new method for the synthesis of isonucleosides is described. The key step in the synthesis was the direct coupling of purine and pyrimidine bases with the cyclic sulfate of a carbohydrate intermediate. This reaction proceeded with high regio specificity and stereospecificity. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：5813 / 5815

页数：3

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