The Rotterdam Study: 2012 objectives and design update

被引：267

作者：

Hofman, Albert ^{[1
]}

van Duijn, Cornelia M. ^{[1
]}

Franco, Oscar H. ^{[1
]}

Ikram, M. Arfan ^{[1
,2
,3
]}

Janssen, Harry L. A. ^{[4
,5
]}

Klaver, Caroline C. W. ^{[1
,9
]}

Kuipers, Ernst J. ^{[4
,5
]}

Nijsten, Tamar E. C. ^{[6
]}

Stricker, Bruno H. Ch. ^{[1
,5
]}

Tiemeier, Henning ^{[1
,7
,8
]}

Uitterlinden, Andre G. ^{[1
,5
]}

Vernooij, Meike W. ^{[1
,3
]}

Witteman, Jacqueline C. M. ^{[1
]}

机构：

[1] Erasmus MC, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands

[2] Erasmus MC, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

[3] Erasmus MC, Dept Radiol, NL-3000 CA Rotterdam, Netherlands

[4] Erasmus MC, Dept Gastroenterol, NL-3000 CA Rotterdam, Netherlands

[5] Erasmus MC, Dept Internal Med, NL-3000 CA Rotterdam, Netherlands

[6] Erasmus MC, Dept Dermatol, NL-3000 CA Rotterdam, Netherlands

[7] Erasmus MC, Dept Psychiat, NL-3000 CA Rotterdam, Netherlands

[8] Erasmus MC, Dept Child & Youth Psychiat, NL-3000 CA Rotterdam, Netherlands

[9] Erasmus MC, Dept Ophthalmol, NL-3000 CA Rotterdam, Netherlands

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 2011年 / 26卷 / 08期

关键词：

Biomarkers; Cardiovascular diseases; Cohort study; Dermatological diseases; Endocrine diseases; Epidemiologic methods; Genetic epidemiology; Liver diseases; Neurological diseases; Oncology; Ophthalmic diseases; Pharmacoepidemiology; Renal diseases; Psychiatric diseases; Respiratory diseases; BONE-MINERAL DENSITY; GENOME-WIDE ASSOCIATION; CORONARY-HEART-DISEASE; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; TYPE-2; DIABETES-MELLITUS; GROWTH-FACTOR-I; ACUTE MYOCARDIAL-INFARCTION; RETINAL VASCULAR CALIBERS; REACTIVE PROTEIN-LEVELS; INTIMA-MEDIA THICKNESS;

D O I：

10.1007/s10654-011-9610-5

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, oncological, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over a 1,000 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

引用

页码：657 / 686

页数：30

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