β-glucans in promoting health:: Prevention against mutation and cancer

被引：229

作者：

Mantovani, Mario S. ^{[1
]}

Bellini, Marilanda F. ^{[2
]}

Angeli, Jose Pedro F. ^{[1
]}

Oliveira, Rodrigo J. ^{[1
]}

Silva, Ariane F. ^{[1
]}

Ribeiro, Lucia R. ^{[3
]}

机构：

[1] Univ Estadual Londrina, Dept Biol Geral, UEL, BR-86051990 Londrina, Parana, Brazil

[2] IBILCE UNESP, Dept Biol, Sao Jose Do Rio Preto, SP, Brazil

[3] UNESP, Programa Posgrad Biol Celular & Mol, Dept Biol, Rio Claro, Brazil

来源：

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH | 2008年 / 658卷 / 03期

基金：

巴西圣保罗研究基金会;

关键词：

beta-glucans; antimutagenesis; biological activities; chemoprevention; anticarcinogenic;

D O I：

10.1016/j.mrrev.2007.07.002

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

The polysaccharides beta-glucans occur as a principal component of the cellular walls. Some microorganisms, such as yeast and mushrooms, and also cereals such as oats and barley, are of economic interest because they contain large amounts of beta-glucans. These substances stimulate the immune system, modulating humoral and cellular immunity, and thereby have beneficial effect in fighting infections (bacterial, viral, fungal and parasitic). beta-Glucans also exhibit hypocholesterolemic and anticoagulant properties. Recently, they have been demonstrated to be anti-cytotoxic, antimutagenic and anti-tumorogenic, making them promising candidate as pharmacological promoters of health. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：154 / 161

页数：8

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