How does temperature play a role in the storage of extracellular vesicles?

被引：50

作者：

Qin Bo ^{[1
]}

Zhang Qi ^{[1
]}

Hu Xi-min ^{[2
]}

Mi Tuo-yang ^{[1
]}

Yu Hai-yang ^{[1
]}

Liu Shen-shen ^{[1
]}

Zhang Bin ^{[1
]}

Tang Mu ^{[1
]}

Huang Ju-fang ^{[1
,3
]}

Xiong Kun ^{[1
,3
]}

机构：

[1] Cent South Univ, Sch Basic Med Sci, Dept Neurobiol & Human Anat, Changsha, Hunan, Peoples R China

[2] Cent South Univ, Xiangya Sch Med, Clin Med 8 Year Program, Changsha, Hunan, Peoples R China

[3] Hunan Key Lab Ophthalmol, Changsha, Hunan, Peoples R China

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2020年 / 235卷 / 11期

基金：

中国国家自然科学基金;

关键词：

cryoprotectants; exosomes; extracellular vesicles; storage; temperature; HUMAN URINARY EXOSOMES; CELL-DERIVED EXOSOMES; PHYSICOCHEMICAL PROPERTIES; MEMBRANE INTEGRITY; STEM-CELLS; CRYOPRESERVATION; PROTEINS; CRYOPROTECTANTS; RNA; DNA;

D O I：

10.1002/jcp.29700

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Extracellular vesicles (EVs) contain specific proteins, lipids, and nucleic acids that can be passed to other cells as signal molecules to alter their function. However, there are many problems and challenges in the conversion and clinical application of EVs. Storage and protection of EVs is one of the issues that need further research. To adapt to potential clinical applications, this type of problem must be solved. This review summarizes the storage practices of EVs in recent years, and explains the impact of temperature on the quality and stability of EVs during storage based on current research, and explains the potential mechanisms involved in this effect as much as possible.

引用

页码：7663 / 7680

页数：18

共 164 条

[1]

Freeze-drying of nanoparticles: Formulation, process and storage considerations [J].

Abdelwahed, Wassim ;

Degobert, Ghania ;

Stainmesse, Serge ;

Fessi, Hatem .

ADVANCED DRUG DELIVERY REVIEWS, 2006, 58 (15) :1688-1713

[2]

Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid [J].

Akers, Johnny C. ;

Ramakrishnan, Valya ;

Yang, Isaac ;

Hua, Wei ;

Mao, Ying ;

Carter, Bob S. ;

Chen, Clark C. .

CANCER BIOMARKERS, 2016, 17 (02) :125-132

[3]

Formation of Supported Bilayers on Silica Substrates [J].

Anderson, Travers H. ;

Min, Younjin ;

Weirich, Kim L. ;

Zeng, Hongbo ;

Fygenson, Deborah ;

Israelachvili, Jacob N. .

LANGMUIR, 2009, 25 (12) :6997-7005

[4]

Malignant effusions and immunogenic tumour-derived exosomes [J].

Andre, F ;

Schartz, NEC ;

Movassagh, M ;

Flament, C ;

Pautier, P ;

Morice, P ;

Pomel, C ;

Lhomme, C ;

Escudier, B ;

Le Chevalier, T ;

Tursz, T ;

Amigorena, S ;

Raposo, G ;

Angevin, E ;

Zitvogel, L .

LANCET, 2002, 360 (9329) :295-305

[5]

Low pH increases the yield of exosome isolation [J].

Ban, Jae-Jun ;

Lee, Mijung ;

Im, Wooseok ;

Kim, Manho .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 461 (01) :76-79

[6]

Long-term storage and safe retrieval of human papillomavirus DNA using FTA elute cards [J].

Barth, Heidi ;

Morel, Adrien ;

Mougin, Christiane ;

Averous, Gerlinde ;

Legrain, Michele ;

Fender, Muriel ;

Risch, Simone ;

Fafi-Kremer, Samira ;

Velten, Michel ;

Oudet, Pierre ;

Baldauf, Jean-Jacques ;

Stoll-Keller, Francoise .

JOURNAL OF VIROLOGICAL METHODS, 2016, 229 :60-65

[7]

Protease-Sensitive, Polymer-Caged Liposomes: A Method for Making Highly Targeted Liposomes Using Triggered Release [J].

Basel, Matthew T. ;

Shrestha, Tej B. ;

Troyer, Deryl L. ;

Bossmann, Stefan H. .

ACS NANO, 2011, 5 (03) :2162-2175

[8]

Best practices for cryopreserving, thawing, recovering, and assessing cells [J].

Baust, John M. ;

Campbell, Lia H. ;

Harbell, John W. .

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2017, 53 (10) :855-871

[9]

Cryoprotectant Toxicity: Facts, Issues, and Questions (vol 18, pg 422, 2015) [J].

Best, Benjamin P. .

REJUVENATION RESEARCH, 2018, 21 (01) :87-87

[10]

TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/ζ complex [J].

Blanchard, N ;

Lankar, D ;

Faure, F ;

Regnault, A ;

Dumont, C ;

Raposo, G ;

Hivroz, C .

JOURNAL OF IMMUNOLOGY, 2002, 168 (07) :3235-3241

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