Cardiorenal syndrome: refining the definition of a complex symbiosis gone wrong

被引:167
作者
Ronco, Claudio [2 ]
House, Andrew A. [3 ]
Haapio, Mikko [1 ]
机构
[1] HUCH Meilahti Hosp, Div Nephrol, Helsinki, Finland
[2] St Bortolo Hosp, Dept Nephrol, Vicenza, Italy
[3] London Hlth Sci Ctr, Div Nephrol, London, ON, Canada
关键词
cardiorenal syndrome; renocardiac syndrome; heart failure; congestive; kidney failure; biological markers;
D O I
10.1007/s00134-008-1017-8
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: The term "cardiorenal syndrome" has generally been reserved for declining renal function in the setting of advanced congestive heart failure. Considering the complex and bi-directional relationship between the heart and the kidneys, we postulate refining the definition to recognize the symbiotic nature of these organs. Discussion: We divide the cardiorenal syndrome into five subtypes: type I, acute cardiorenal syndrome; type II, chronic cardiorenal syndrome; type III, acute renocardiac syndrome; type IV, chronic renocardiac syndrome; and type V, secondary cardiorenal syndrome. Conclusions: As early recognition of dysfunction in one organ may prove important in mitigating the spiral of co-dysfunction in both, the need for early and treatment-guiding biomarkers, along with their characteristics, are also discussed.
引用
收藏
页码:957 / 962
页数:6
相关论文
共 34 条
[1]   Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death [J].
Apple, FS ;
Murakami, MM ;
Pearce, LA ;
Herzog, CA .
CLINICAL CHEMISTRY, 2004, 50 (12) :2279-2285
[2]   Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria [J].
Bellomo, Rinaldo ;
Kellum, John A. ;
Ronco, Claudio .
INTENSIVE CARE MEDICINE, 2007, 33 (03) :409-413
[3]   Kidney-heart interactions: Epidemiology, pathogenesis, and treatment [J].
Berl, Tomas ;
Henrich, William .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 1 (01) :8-18
[4]  
BONGARTZ LG, 2005, INT J ARTIF ORGANS, V30, P564
[5]   Prognostic potential of brain natriuretic peptide (BNP) in predialysis chronic kidney disease patients [J].
Carr, SJ ;
Bavanandan, S ;
Fentum, B ;
Ng, L .
CLINICAL SCIENCE, 2005, 109 (01) :75-82
[6]  
Deswal A, 2001, CIRCULATION, V103, P2055
[7]   Acute renal failure after successful cardiopulmonary resuscitation [J].
Domanovits, H ;
Schillinger, M ;
Müllner, M ;
Thoennissen, J ;
Sterz, F ;
Zeiner, A ;
Druml, W .
INTENSIVE CARE MEDICINE, 2001, 27 (07) :1194-1199
[8]  
Fort Joan, 2005, Kidney Int Suppl, pS25, DOI 10.1111/j.1523-1755.2005.09906.x
[9]   BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy [J].
Gottlieb, SS ;
Brater, DC ;
Thomas, I ;
Havranek, E ;
Bourge, R ;
Goldman, S ;
Dyer, F ;
Gomez, M ;
Bennett, D ;
Ticho, B ;
Beckman, E ;
Abraham, WT .
CIRCULATION, 2002, 105 (11) :1348-1353
[10]   Diagnostic and prognostic evaluation of left ventricular systolic heart failure by plasma N-terminal pro-brain natriuretic peptide concentrations in a large sample of the general population [J].
Groenning, BA ;
Raymond, I ;
Hildebrandt, PR ;
Nilsson, JC ;
Baumann, M ;
Pedersen, F .
HEART, 2004, 90 (03) :297-303