Skeleton-selective fluorescent chemosensor based on cyclodextrin bearing a 4-amino-7-nitrobenz-2-oxa-1,3-diazole moiety

被引：32

作者：

Ikeda, H ^{[1
]}

Murayama, T ^{[1
]}

Ueno, A ^{[1
]}

机构：

[1] Tokyo Inst Technol, Grad Sch Biosci & Biotechnol, Dept Bioengn, Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2005年 / 3卷 / 23期

关键词：

D O I：

10.1039/b508477f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new type of fluorescent chemosensor, based on modified cyclodextrins bearing the fluorophore unit NBD-amine, was prepared. One of these new chemosensors, NC0 beta CD, is sensitive to adamantane and borneol derivatives, which have a comparatively spherical shape that fits the beta-CD cavity, but is not sensitive to bile acids, which are strongly bound by the native beta-CD. Even in the presence of a bile acid, NC0 beta CD can detect 1-adamantanol. Another of this new type of chemosensors, NC0 gamma CD, is sensitive to bile acids but not to adamantane derivatives. The response of the new type of chemosensors to a guest was an increase in the. uorescence intensity.

引用

页码：4262 / 4267

页数：6

共 19 条

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