A concise, stereoselective synthesis of (+/-)-geissoschizine

被引：18

作者：

Bennasar, ML

Jimenez, JM

Sufi, BA

Bosch, J

机构：

[1] Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(96)02097-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stereocontrolled synthesis of (+/-)-geissoschizine, involving the addition of the enolate derived from 1-acetylindole to pyridinium salt 2, cyclization of the resultant 1,4-dihydropyridine stereoselective elaboration of the E-ethylidene substituent, closure of C ring by Pummerer reaction, and methanolysis of the resulting pentacyclic lactam, is reported. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：9105 / 9106

页数：2

共 13 条

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