Recovery of electrophysiological parameters after conversion of atrial fibrillation

被引：18

作者：

Sato, T ^{[1
]}

Mitamura, H ^{[1
]}

Kurita, Y ^{[1
]}

Takeshita, A ^{[1
]}

Shinagawa, K ^{[1
]}

Miyoshi, S ^{[1
]}

Kanki, H ^{[1
]}

Hara, M ^{[1
]}

Takatsuki, S ^{[1
]}

Soejima, K ^{[1
]}

Ogawa, S ^{[1
]}

机构：

[1] Keio Univ, Sch Med, Dept Med, Cardiopulm Div,Shinjuku Ku, Tokyo 1608582, Japan

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2001年 / 79卷 / 2-3期

关键词：

atrial fibrillation; electrical cardioversion; atrial effective refractory period; P wave duration;

D O I：

10.1016/S0167-5273(01)00419-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated the recovery of electrophysiological parameters from electrical remodeling after conversion of chronic lone atrial fibrillation in humans. Clinical studies have shown that the longer atrial fibrillation lasts, the more difficult it becomes to maintain the sinus rhythm after cardioversion. To explore the effects of the duration of atrial fibrillation on changes of electrophysiological parameters after conversion, we determined the atrial effective refractory period and P wave duration during right atrial pacing at 1 and 24 h after electrical cardioversion in 15 patients with chronic lone atrial fibrillation (median duration, 6 months). By 24 h after cardioversion, the effective refractory period at a pacing cycle length of 600 ms increased from 225 +/- 19 to 254 +/- 27 ms. However, the P wave duration did not decrease significantly 24 h after conversion. As the duration of atrial fibrillation became longer, the prolongation of effective refractory period was more delayed (P < 0.001, r = 0.82), and the shortening of P wave duration was significantly smaller within 24 h after cardioversion (P < 0.001, r = 0.67). After cardioversion of chronic lone atrial fibrillation, the recovery of shortened atrial refractoriness and prolonged intraatrial conduction time is dependent on the duration of preexisting atrial fibrillation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：183 / 189

页数：7

共 29 条

[1] FAILURE IN THE RATE ADAPTATION OF THE ATRIAL REFRACTORY PERIODS - NEW PARAMETER TO ASSESS ATRIAL VULNERABILITY [J].