A new synthesis of (-)-debromoflustramine B, (+)-ent-debromoflustramine B and (+)-debromoflustramide B

被引：33

作者：

Cardoso, AS

Srinivasan, N

Lobo, AM

Prabhakar, S

机构：

[1] Univ Nova Lisboa, Ctr Quim Fina & Biotecnol, Dept Quim, Seccao Quim Organ Aplicada, P-2829 Monte De Caparica, Portugal

[2] Univ Nova Lisboa, SINTOR, UNINOVA, P-2829 Monte De Caparica, Portugal

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 38期

关键词：

alkaloids; amino alcohols; cyclization; indoles; oxygenation;

D O I：

10.1016/S0040-4039(01)01359-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of (-)-debromoflustramine B is reported. Appropriate structural modifications of an optically pure Barton ester, obtained in five steps from N-acetyl-L-tryptophan methyl ester, lead to the alkaloid. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6663 / 6666

页数：4

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