Stereoselective epoxidation of cyclic alkenes using m-CPBA and Oxone®/trifluoroacetone -: a comparison

被引：16

作者：

de Sousa, SE ^{[1
]}

O'Brien, P ^{[1
]}

Pilgram, CD ^{[1
]}

Roder, D ^{[1
]}

Towers, TD ^{[1
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 02期

关键词：

epoxidation; diastereoselection; dioxiranes;

D O I：

10.1016/S0040-4039(98)02320-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A comparison of the observed diastereoselectivity of epoxidation of cyclic alkenes using m-CPBA and Oxone(R)/trifluoroacetone is reported. The results indicate that dioxirane epoxidations are sterically controlled and provide a crude model for determination of whether hydrogen bonding is operating in the m-CPBA epoxidations. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：391 / 392

页数：2

共 11 条

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