Total synthesis of nigellicine and nigeglanine hydrobromide

被引：34

作者：

Elliott, EL ^{[1
]}

Bushell, SM ^{[1
]}

Cavero, M ^{[1
]}

Tolan, B ^{[1
]}

Kelly, TR ^{[1
]}

机构：

[1] Boston Coll, EF Merkert Chem Ctr, Chestnut Hill, MA 02467 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 12期

关键词：

D O I：

10.1021/ol050769m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The first syntheses of the pyridazinoindazolium alkaloids nigellicine and nigeglanine hydrobromide via a common intermediate are described. Ortho-lithiation/acylation and the direct amination of an isatin ring system are the key steps in the synthesis.

引用

页码：2449 / 2451

页数：3

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