Prevalence of and risk factors for abdominal aortic aneurysms in a population-based study - The Tromso study

被引:448
作者
Singh, K [1 ]
Bonaa, KH
Jacobsen, BK
Bjork, L
Solberg, S
机构
[1] Univ Tromso Hosp, Dept Radiol, N-9038 Tromso, Norway
[2] Univ Tromso, Sch Med, Inst Community Med, Tromso, Norway
[3] Univ Tromso Hosp, Dept Thorac & Cardiovasc Surg, N-9012 Tromso, Norway
关键词
aneurysm; aorta; abdominal; lipoproteins; HDL cholesterol; prevalence; risk factors; ultrasonography;
D O I
10.1093/aje/154.3.236
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In a population-based study of 6,386 men and women aged 25-84 years in Tromso, Norway, in 1994-1995, the authors assessed the age- and sex-specific distribution of the abdominal aortic diameter and the prevalence of and risk factors for abdominal aortic aneurysm. Renal and infrarenal aortic diameters were measured with ultrasound. The mean infrarenal aortic diameter increased with age. The increase was more pronounced in men than in women. The age-related increase in the median diameter was less than that in the mean diameter. An aneurysm was present in 263 (8.9%) men and 74 (2.2%) women (p < 0.001). The prevalence of abdominal aortic aneurysm increased with age. No person aged less than 48 years was found with an abdominal aortic aneurysm. Persons who had smoked for more than 40 years had an odds ratio of 8.0 for abdominal aortic aneurysm (95% confidence interval: 5.0, 12.6) compared with never smokers. Low serum high density lipoprotein cholesterol was associated with an increased risk for abdominal aortic aneurysm. Other factors associated with abdominal aortic aneurysm were a high level of plasma fibrinogen and a low blood platelet count. Antihypertensive medication (ever use) was significantly associated with abdominal aortic aneurysm, but high systolic blood pressure was a risk factor in women only. This study indicates that risk factors for atherosclerosis are also associated with increased risk for abdominal aortic aneurysm.
引用
收藏
页码:236 / 244
页数:9
相关论文
共 45 条
[1]   Risk factors for abdominal aortic aneurysms in older adults enrolled in the cardiovascular health study [J].
Alcorn, HG ;
Wolfson, SK ;
SuttonTyrrell, K ;
Kuller, LH ;
OLeary, D .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1996, 16 (08) :963-970
[2]   OPERATIVE MORTALITY AND LONG-TERM RELATIVE SURVIVAL OF PATIENTS OPERATED ON FOR ASYMPTOMATIC ABDOMINAL AORTIC-ANEURYSM [J].
AUNE, S ;
AMUNDSEN, SR ;
EVJENSVOLD, J ;
TRIPPESTAD, A .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 1995, 9 (03) :293-298
[3]   Mortality from ruptured abdominal aortic aneurysm in Wales [J].
Basnyat, PS ;
Biffin, AHB ;
Moseley, LG ;
Hedges, AR ;
Lewis, MH .
BRITISH JOURNAL OF SURGERY, 1999, 86 (06) :765-770
[4]   Incidence and prevalence of abdominal aortic aneurysms, estimated by necropsy studies and population screening by ultrasound [J].
Bengtsson, H ;
Sonesson, B ;
Bergqvist, D .
ABDOMINAL AORTIC ANEURYSM: GENETICS, PATHOPHYSIOLOGY, AND MOLECULAR BIOLOGY, 1996, 800 :1-24
[5]   Soluble adhesion molecules, endothelial markers and atherosclerosis risk factors in abdominal aortic aneurysm: a comparison with claudicants and healthy controls [J].
Blann, AD ;
Devine, C ;
Amiral, J ;
McCollum, CN .
BLOOD COAGULATION & FIBRINOLYSIS, 1998, 9 (06) :479-484
[6]  
BLICHER, 1840, HAANDBIBLIOTHEK LOEG
[7]  
BONAA KH, 1992, CIRCULATION, V86, P394
[8]  
Cao P, 1999, Cardiologia, V44, P711
[9]  
COLLIN J, 1988, LANCET, V2, P613
[10]   AGE-RELATED-CHANGES IN THE ABDOMINAL-AORTA SHOWN BY COMPUTED-TOMOGRAPHY [J].
DIXON, AK ;
LAWRENCE, JP ;
MITCHELL, JRA .
CLINICAL RADIOLOGY, 1984, 35 (01) :33-37