Communicating science to the public: MMR vaccine and autism

被引:62
作者
Offit, PA
Coffin, SE
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Sch Med, Div Infect Dis, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA
关键词
MMR; autism; intestinal inflammation;
D O I
10.1016/S0264-410X(03)00532-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Media attention and consequent public concerns about vaccine safety followed publication of a small case-series of children who developed autism after receipt of the measles-mumps-rubella (MMR) vaccine. Many well-controlled studies performed subsequently found no evidence that MMR vaccine causes autism. However, despite these studies, some parents remain concerned that the MMR vaccine is not safe. We will discuss the origins of the hypothesis that the MMR vaccine causes autism, studies performed to test the hypothesis, how these studies have been communicated to the public, and some suggested strategies for how this communication can be improved. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 48 条
[1]  
Afzal MA, 1998, J MED VIROL, V55, P243, DOI 10.1002/(SICI)1096-9071(199807)55:3<243::AID-JMV11>3.0.CO
[2]  
2-H
[3]   Hepatitis B vaccination and the risk of multiple sclerosis [J].
Ascherio, A ;
Zhang, SM ;
Hernán, MA ;
Olek, MJ ;
Coplan, PM ;
Brodovicz, K ;
Walker, AM .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (05) :327-332
[4]  
BART KJ, 1991, JAMA-J AM MED ASSOC, V266, P1547
[5]   Lack of association between receipt of conjugate Haemophilus influenzae type b vaccine (HbOC) in infancy and risk of type 1 (juvenile onset) diabetes:: Long term follow-up of the HbOC efficacy trial cohort [J].
Black, SB ;
Lewis, E ;
Shinefield, HR ;
Fireman, B ;
Ray, P ;
DeStefano, F ;
Chen, R .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2002, 21 (06) :568-569
[6]  
BOSELEY S, 2001, GUARDIAN 0105
[7]  
Chadwick N, 1998, J MED VIROL, V55, P305, DOI 10.1002/(SICI)1096-9071(199808)55:4&lt
[8]  
305::AID-JMV9&gt
[9]  
3.0.CO
[10]  
2-4