Does properdin crosslink the cellular and the humoral immune response?

被引：86

作者：

Schwaeble, WJ ^{[1
]}

Reid, KBM

机构：

[1] Univ Leicester, Dept Microbiol & Immunol, Leicester LE1 9HN, Leics, England

[2] Univ Oxford, Dept Biochem, MRC, Immunochem Unit, Oxford OX1 3QU, England

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 01期

关键词：

D O I：

10.1016/S0167-5699(98)01376-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Properdin, the only known positive regulator of complement activation, is produced by cells of the monocyte-macrophage, T-cell and granulocyte lineages. Complement activation products have an established role in the cellular immune response. However, here, Wilhelm Schwaeble and Kenneth Reid discuss current data demonstrating that leukocytes form a positive feedback loop of activation by properdin release.

引用

页码：17 / 21

页数：5

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