Ion suppression in mass spectrometry

被引：1270

作者：

Annesley, TM ^{[1
]}

机构：

[1] Univ Michigan, Med Ctr, Dept Pathol, Ann Arbor, MI 48109 USA

来源：

CLINICAL CHEMISTRY | 2003年 / 49卷 / 07期

关键词：

D O I：

10.1373/49.7.1041

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 [基础医学];

摘要：

Whenever mass spectrometric assays are developed, ion suppression studies should be performed using expected physiologic concentrations of the analyte under investigation. (C) 2003 American Association for Clinical Chemistry.

引用

页码：1041 / 1044

页数：4

共 16 条

[1]

ENHANCED SENSITIVITY FOR PEPTIDE-MAPPING WITH ELECTROSPRAY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY IN THE PRESENCE OF SIGNAL SUPPRESSION DUE TO TRIFLUOROACETIC ACID-CONTAINING MOBILE PHASES [J].

APFFEL, A ;

FISCHER, S ;

GOLDBERG, G ;

GOODLEY, PC ;

KUHLMANN, FE .

JOURNAL OF CHROMATOGRAPHY A, 1995, 712 (01) :177-190

[2]

BEATO BD, 2000, CURR SEP, V19, P55

[3]

Bonfiglio R, 1999, RAPID COMMUN MASS SP, V13, P1175, DOI 10.1002/(SICI)1097-0231(19990630)13:12<1175::AID-RCM639>3.3.CO

[4]

2-S

[5]

FACTORS AFFECTING ELECTROSPRAY-IONIZATION OF EFFLUENTS CONTAINING TRIFLUOROACETIC-ACID FOR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY [J].

ESHRAGHI, J ;

CHOWDHURY, SK .

ANALYTICAL CHEMISTRY, 1993, 65 (23) :3528-3533

[6]

Peptide-mass profiles of polyvinylidene difluoride-bound proteins by matrix-assisted laser desorption ionization time-of-flight mass spectrometry in the presence of nonionic detergents [J].

Gharahdaghi, F ;

Kirchner, M ;

Fernandez, J ;

Mische, SM .

ANALYTICAL BIOCHEMISTRY, 1996, 233 (01) :94-99

[7]

Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry [J].

Hsieh, YS ;

Chintala, M ;

Mei, H ;

Agans, J ;

Brisson, JM ;

Ng, K ;

Korfmacher, WA .

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2001, 15 (24) :2481-2487

[8]

Mechanistic investigation of ionization suppression in electrospray ionization [J].

King, R ;

Bonfiglio, R ;

Fernandez-Metzler, C ;

Miller-Stein, C ;

Olah, T .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2000, 11 (11) :942-950

[9]

Improvement in precision of the liquid chromatographic-electrospray ionization tandem mass spectrometric analysis of 3′-C-ethynylcytidine in rat plasma [J].

Kitamura, R ;

Matsuoka, K ;

Matsushima, E ;

Kawaguchi, Y .

JOURNAL OF CHROMATOGRAPHY B, 2001, 754 (01) :113-119

[10]

The dominance of arginine-containing peptides in MALDI-derived tryptic mass fingerprints of proteins [J].

Krause, E ;

Wenschuh, H ;

Jungblut, PR .

ANALYTICAL CHEMISTRY, 1999, 71 (19) :4160-4165

← 1 2 →