Properties of stimulus-dependent synchrony in retinal ganglion cells

被引:6
作者
Chatterjee, Susmita [1 ]
Merwine, David K. [1 ]
Amthor, Franklin R. [3 ]
Grzywacz, Norberto M. [1 ,2 ]
机构
[1] Univ So Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA
[2] Univ So Calif, Grad Program Neurosci, Los Angeles, CA 90089 USA
[3] Univ Alabama Birmingham, Dept Psychol, Birmingham, AL 35294 USA
关键词
rabbit retina; ganglion cell; synchronous spikes; stimulus-dependent correlation; amacrine-cell network;
D O I
10.1017/S0952523807070757
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Neighboring retinal ganglion cells often spike synchronously, but the possible function and mechanism of this synchrony is unclear. Recently, the strength of the fast correlation between ON-OFF directionally selective cells of the rabbit retina was shown to be stimulus dependent. Here, we extend that study, investigating stimulus-dependent correlation among multiple ganglion-cell classes, using multi-electrode recordings. Our results generalized those for directionally selective cells. All cell pairs exhibiting significant spike synchrony did it for an extended edge but rarely for full-field stimuli. The strength of this synchrony did not depend on the amplitude of the response and correlations could be present even when the cells' receptive fields did not overlap. In addition, correlations tended to be orientation selective in a manner predictable by the relative positions of the receptive fields. Finally, extended edges and full-field stimuli produced significantly greater and smaller correlations than predicted by chance respectively. We propose an amacrine-network model for the enhancement and depression of correlation. Such an apparently purposeful control of correlation adds evidence for retinal synchrony playing a functional role it] vision.
引用
收藏
页码:827 / 843
页数:17
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