Chemoselective addition of Grignard reagents to alkoxycarbonylalkyl-N-imidazolium-N-methyl amides: Synthesis of 4-oxo and homologous esters

被引：7

作者：

delasHeras, MA ^{[1
]}

Vaquero, JJ ^{[1
]}

GarciaNavio, JL ^{[1
]}

AlvarezBuilla, J ^{[1
]}

机构：

[1] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALCALA DE HENARES, MADRID, SPAIN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(97)00159-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for the synthesis of Core and homologous esters is achieved by metalation of alkoxycarbonylalkyl-N-imidazolium-N-methyl amides with lequiv of LDA followed by highly chemoselective addition of 1 equiv of a Grignard reagent. (C) 1997 Elsevier Science Ltd.

引用

页码：1817 / 1820

页数：4

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