EUS-guided fine-needle aspiration of the pancreas: evaluation of pancreatitis as a complication

被引:111
作者
Gress, F
Michael, H
Gelrud, D
Patel, P
Gottlieb, K
Singh, F
Grendell, J
机构
[1] SUNY Stony Brook, Winthrop Univ Hosp, Sch Med, Div Gastroenterol Hepatol & Nutr, Mineola, NY 11501 USA
[2] SUNY Stony Brook, Hlth Sci Ctr, Mineola, NY 11501 USA
关键词
D O I
10.1067/mge.2002.129602
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: EUS-guided fine-needle aspiration is rapidly becoming the procedure of choice for the diagnostic evaluation of pancreatic masses. Acute pancreatitis has been reported after EUS-guided fine-needle aspiration of the pancreas. This study evaluated the effect of EUS-guided fine-needle aspiration on the pancreas by serial measurement of amylase and lipase levels and determining the frequency of acute pancreatitis after EUS-guided fine-needle aspiration of pancreatic masses. Methods: In 100 consecutive patients referred for EUS-guided fine-needle aspiration of a pancreatic mass, amylase and lipase levels were determined immediately before and within 2 hours after the procedure. Additionally, patients were questioned as to the occurrence of symptoms of acute pancreatitis within 48 hours after EUS-guided fine-needle aspiration. Results: For 2 of 100 patients (2%) there was clinical and biochemical evidence of acute pancreatitis after EUS-guided fine-needle aspiration. Both patients had a history of recent pancreatitis. In addition, there was a significant increase in postprocedure lipase levels (p = 0.40) compared with amylase levels in this patient subset. Conclusion: The frequency of acute pancreatitis after EUS-guided fine-needle aspiration of the pancreas was 2% in this study. A history of recent pancreatitis appears to be a potential risk factor. Amylase and lipase levels can be elevated after EUS-guided fine-needle aspiration and in most cases have no clinical significance.
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页码:864 / 867
页数:4
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