Epidemiology of brain tumors

被引:443
作者
Fisher, James L.
Schwartzbaum, Judith A.
Wrensch, Margaret
Wiemels, Joseph L.
机构
[1] Arthur G James Canc Hosp, Richard J Solove Res Inst, Columbus, OH 43221 USA
[2] Ohio State Univ, Comprehens Canc Ctr, Columbus, OH USA
[3] Ohio State Univ, Coll Publ Hlth, Div Epidemiol, Columbus, OH 43210 USA
[4] Karolinska Inst, Inst Environm Med, Stockholm, Sweden
[5] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA
[6] Univ Calif San Francisco, Dept Epidemiol & Biostats, San Francisco, CA 94143 USA
[7] Univ Calif San Francisco, Dept Epidemiol & Biostats, Div Canc Epidemiol, San Francisco, CA 94143 USA
关键词
D O I
10.1016/j.ncl.2007.07.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Brain tumors seemed to have increased in incidence over the past 30 years, but the rise probably results from use of new neuroimaging techniques. Treatments have not improved prognosis for rapidly fatal brain tumors. Established brain tumor risk factors (exposure to ionizing radiation, rare mutations of penetrant genes, and familial history) explain only a small proportion of brain tumors, and only one of these potentially is modifiable. Genetic and environmental characteristics likely play a role in familial aggregation of glioma and these factors are not identified. New concepts in brain tumor etiology and clinical management are the goal of research, with an aim at eradicating this devastating disease.
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收藏
页码:867 / +
页数:25
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