Chiral discrimination by modified cyclodextrins

被引：152

作者：

Easton, CJ ^{[1
]}

Lincoln, SF ^{[1
]}

机构：

[1] UNIV ADELAIDE, DEPT CHEM, ADELAIDE, SA 5005, AUSTRALIA

来源：

CHEMICAL SOCIETY REVIEWS | 1996年 / 25卷 / 03期

关键词：

NUCLEAR-MAGNETIC-RESONANCE; BETA-CYCLODEXTRIN; ALPHA-CYCLODEXTRIN; AQUEOUS-SOLUTION; COPPER(II) COMPLEX; ENZYME INHIBITION; AMINO-ACIDS; CHROMATOGRAPHIC SEPARATION; STEREOSPECIFIC REACTION; MOLECULAR RECOGNITION;

D O I：

10.1039/cs9962500163

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Naturally occuring cyclodextrins show only limited enantioselectivity in their interactions with chiral guests, because they form inclusion complexes in which there is only limited interaction between chiral centres of the cyclodextrin and those of the guest. As the extent of interaction between these groups is increased, as a result of modification to the cyclodextrin, the stereoselectivity is often increased. Additional secondary bonding interactions, complexation to metallocyclodextrins and covalent host-guest interactions all lead to enhanced chiral discrimination.

引用

页码：163 / +

页数：1

共 53 条

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