NK cell recognition

被引:2152
作者
Lanier, LL [1 ]
机构
[1] Univ Calif San Francisco, Sch Med, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Sch Med, Canc Res Inst, San Francisco, CA 94143 USA
关键词
innate immunity; immune receptors; signal transduction;
D O I
10.1146/annurev.immunol.23.021704.115526
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
引用
收藏
页码:225 / 274
页数:50
相关论文
共 369 条
  • [1] Murine cytomegalovirus with a transposon Insertional mutation at open reading frame m155 is deficient in growth and virulence in mice
    Abenes, G
    Chan, KR
    Lee, M
    Haghjoo, E
    Zhu, JM
    Zhou, TH
    Zhan, XY
    Liu, FY
    [J]. JOURNAL OF VIROLOGY, 2004, 78 (13) : 6891 - 6899
  • [2] IDENTIFICATION OF A TAP-DEPENDENT LEADER PEPTIDE RECOGNIZED BY ALLOREACTIVE T-CELLS SPECIFIC FOR A CLASS IB ANTIGEN
    ALDRICH, CJ
    DECLOUX, A
    WOODS, AS
    COTTER, RJ
    SOLOSKI, MJ
    FORMAN, J
    [J]. CELL, 1994, 79 (04) : 649 - 658
  • [3] Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells
    Allan, DSJ
    Colonna, M
    Lanier, LL
    Churakova, TD
    Abrams, JS
    Ellis, SA
    McMichael, AJ
    Braud, VM
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (07) : 1149 - 1155
  • [4] CD3-NEGATIVE NATURAL-KILLER CELLS EXPRESS ZETA-TCR AS PART OF A NOVEL MOLECULAR-COMPLEX
    ANDERSON, P
    CALIGIURI, M
    RITZ, J
    SCHLOSSMAN, SF
    [J]. NATURE, 1989, 341 (6238) : 159 - 162
  • [5] Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors
    André, P
    Castriconi, R
    Espéli, M
    Anfossi, N
    Juarez, T
    Hue, S
    Conway, H
    Romagné, F
    Dondero, A
    Nanni, M
    Caillat-Zucman, S
    Raulet, DH
    Bottino, C
    Vivier, E
    Moretta, A
    Paul, P
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 2004, 34 (04) : 961 - 971
  • [6] ARAMBURU J, 1990, J IMMUNOL, V144, P3238
  • [7] Specific recognition of virus-infected cells by paired NK receptors
    Arase, H
    Lanier, LL
    [J]. REVIEWS IN MEDICAL VIROLOGY, 2004, 14 (02) : 83 - 93
  • [8] Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors
    Arase, H
    Mocarski, ES
    Campbell, AE
    Hill, AB
    Lanier, LL
    [J]. SCIENCE, 2002, 296 (5571) : 1323 - 1326
  • [9] Interferon gamma production by natural killer (NK) cells and NK1.1(+) T cells upon NKR-P1 cross-linking
    Arase, H
    Arase, N
    Saito, T
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (05) : 2391 - 2396
  • [10] Association with FcRγ is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells
    Arase, N
    Arase, H
    Park, SY
    Ohno, H
    Ra, C
    Saito, T
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (12) : 1957 - 1963