B-arrestins: Multifunctional cellular mediators

被引:35
作者
Barki-Harrington, Liza [1 ]
Rockman, Howard A. [2 ,3 ,4 ]
机构
[1] Univ Haifa, Dept Biol, IL-31999 Haifa, Israel
[2] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Cell Biol, Durham, NC 27710 USA
[4] Duke Univ, Med Ctr, Dept Mol Genet, Durham, NC 27710 USA
关键词
D O I
10.1152/physiol.00042.2007
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Initially thought to play a role only in G-protein-coupled receptor desensitization, beta-arrestins are ascribed with new roles such as scaffolding and signaling proteins by their own right. This review explores the many functions of beta-arrestins, with an emphasis on their recently identified role as regulators of receptor signaling.
引用
收藏
页码:17 / 22
页数:6
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