Status epilepticus with neuron-reactive serum antibodies: Response to plasma exchange

被引：21

作者：

Lousa, M

Sanchez-Alonso, S

Rodriguez-Diaz, R

Dalmau, J

机构：

[1] Hosp Ramon y Cajal, Serv Neurol, Unidad Cuidados Intensiv, 28034 Madrid, Spain

[2] Cornell Univ, Med Ctr, Mem Sloan Kettering Canc Ctr, Dept Neurol, New York, NY USA

来源：

NEUROLOGY | 2000年 / 54卷 / 11期

关键词：

status epilepticus; Rasmussen's encephalitis; plasma exchange; glutamate receptor; antibodies to GluR3;

D O I：

10.1212/WNL.54.11.2163

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors report a patient with partial and secondarily generalized status epilepticus who required 70 days of general anesthesia for seizure control. Although antiepileptic medications failed to control the seizures, they resolved with plasma exchange. The patient's serum reacted with rat cerebral cortex, hippocampus, and cerebellum, but not with cells expressing the glutamate receptor GluR3. These findings suggest an immune response against neuronal antigens other than GluR3.

引用

收藏

页码：2163 / 2165

页数：3

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