Structure of the O-polysaccharide of Proteus mirabilis OC (CCUG 10702) from a new proposed Proteus serogroup O75

被引：10

作者：

Zablotni, A

Perepelov, AV

Knirel, YA

Sidorczyk, Z ^{[1
]}

机构：

[1] Univ Lodz, Inst Microbiol & Immunol, PL-90237 Lodz, Poland

[2] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia

来源：

CARBOHYDRATE RESEARCH | 2005年 / 340卷 / 11期

基金：

俄罗斯基础研究基金会;

关键词：

Proteus mirabilis; lipopolysaccharide; O-polysaccharide; O-serogroup; epitope;

D O I：

10.1016/j.carres.2005.05.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

A neutral O-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of Proteus mirabilis OC (CCUG 10702) and studied by sugar and methylation analyses and H-1 and C-13 NMR spectroscopy. The following structure of the tetrasaccharide repeating unit of the polysaccharide was established: [GRAPHICS] Based on the unique structure of the O-polysaccharide and serological data, we propose classifying P. mirabilis OC (CCUG 10702) into a new separate Proteus serogroup O75. A weak cross-reaction of O-antiserum against P. mirabilis OC with the lipopolysaccharide of P. mirabilis O49 was accounted for by a similarity in the O-polysaccharide structures. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1908 / 1913

页数：6

共 24 条

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[2]

C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF MONOSACCHARIDES [J].