Synthesis of Novel 2-Alkoxy(aralkoxy)-4H-[1,2,4]triazolo[1,5-a] quinazolin-5-ones Starting with Dialkyl-N-Cyanoimidocarbonates

被引：13

作者：

Al-Salahi, Rashad ^{[1
]}

Geffken, Detlef ^{[2
]}

机构：

[1] King Saud Univ, Dept Pharmaceut Chem, Coll Pharm, Riyadh 11451, Saudi Arabia

[2] Univ Hamburg, Inst Pharm, Dept Chem, D-20146 Hamburg, Germany

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 03期

关键词：

H-1-ANTIHISTAMINIC AGENTS; ANTAGONISTS; SERIES;

D O I：

10.1002/jhet.574

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

A novel series of 2-alkoxy(aralkoxy)-4H-[1,2,4]triazolo[1,5-a]quinazolines were synthesized employing N-cyanoimidocarbonates and 2-hydrazinobenzoic acid as building blocks. Chemical transformation of the inherent lactam moiety in the targeted 2-alkoxy(aralkoxy)[1,2,4] triazolo[1,5-a] quinazolines was offered access to a variety of derivatives.

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收藏

页码：656 / 662

页数：7

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