Panretinal Photocoagulation for Proliferative Diabetic Retinopathy

被引:113
作者
Bressler, Neil M. [2 ]
Beck, Roy W. [3 ]
Ferris, Frederick L., III [1 ]
机构
[1] NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA
[2] Johns Hopkins Univ, Sch Med, Dept Ophthalmol, Baltimore, MD 21205 USA
[3] Jaeb Ctr Hlth Res, Tampa, FL USA
关键词
ENDOTHELIAL GROWTH-FACTOR; IRIS NEOVASCULARIZATION; LASER PHOTOCOAGULATION; INTRAVITREAL INJECTION; RETINAL NEOVASCULARIZATION; BEVACIZUMAB AVASTIN; TRANSIENT MYOPIA; FOLLOW-UP; INHIBITION;
D O I
10.1056/NEJMct0908432
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
A 55-year-old man with a 20-year history of type 2 diabetes mellitus was referred to a retina specialist after noticing a few black floaters in his left eye for the preceding week. His glycated hemoglobin level was 8.2%. He had no history of laser treatment for proliferative diabetic retinopathy in either eye. Ophthalmoscopic examination of the right eye showed venous beading, intraretinal microvascular abnormalities, and no macular edema. Ophthalmoscopic examination of the left eye showed extensive neovascularization of the disk, consisting of new vessels extending beyond the optic disk in all directions (Fig. 1A). The retina specialist diagnosed severe nonproliferative diabetic retinopathy in the right eye and high-risk proliferative diabetic retinopathy in the left eye, with no macular edema in either eye. The specialist recommended prompt initiation of panretinal photocoagulation in the left eye.
引用
收藏
页码:1520 / 1526
页数:7
相关论文
共 46 条
[1]
Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals [J].
Adamis, AP ;
Altaweel, M ;
Bressler, NM ;
Cunningham, ET ;
Davis, MD ;
Goldbaum, M ;
Gonzales, C ;
Guyer, DR ;
Katz, B ;
Patel, M .
OPHTHALMOLOGY, 2006, 113 (01) :23-28
[2]
INCREASED VASCULAR ENDOTHELIAL GROWTH-FACTOR LEVELS IN THE VITREOUS OF EYES WITH PROLIFERATIVE DIABETIC-RETINOPATHY [J].
ADAMIS, AP ;
MILLER, JW ;
BERNAL, MT ;
DAMICO, DJ ;
FOLKMAN, J ;
YEO, TK ;
YEO, KT .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1994, 118 (04) :445-450
[3]
Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate [J].
Adamis, AP ;
Shima, DT ;
Tolentino, MJ ;
Gragoudas, ES ;
Ferrara, N ;
Folkman, J ;
DAmore, PA ;
Miller, JW .
ARCHIVES OF OPHTHALMOLOGY, 1996, 114 (01) :66-71
[4]
Angiogenic pathways in diabetic retinopathy [J].
Aiello, LP .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (08) :839-841
[5]
SUPPRESSION OF RETINAL NEOVASCULARIZATION IN-VIVO BY INHIBITION OF VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) USING SOLUBLE VEGF-RECEPTOR CHIMERIC PROTEINS [J].
AIELLO, LP ;
PIERCE, EA ;
FOLEY, ED ;
TAKAGI, H ;
CHEN, H ;
RIDDLE, L ;
FERRARA, N ;
KING, GL ;
SMITH, LEH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (23) :10457-10461
[6]
VASCULAR ENDOTHELIAL GROWTH-FACTOR IN OCULAR FLUID OF PATIENTS WITH DIABETIC-RETINOPATHY AND OTHER RETINAL DISORDERS [J].
AIELLO, LP ;
AVERY, RL ;
ARRIGG, PG ;
KEYT, BA ;
JAMPEL, HD ;
SHAH, ST ;
PASQUALE, LR ;
THIEME, H ;
IWAMOTO, MA ;
PARK, JE ;
NGUYEN, HV ;
AIELLO, LM ;
FERRARA, N ;
KING, GL .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (22) :1480-1487
[7]
Amano S, 1998, INVEST OPHTH VIS SCI, V39, P18
[8]
[Anonymous], 1995, DIABETES, V44, P968
[9]
[Anonymous], 1976, Am J Ophthalmol, V81, P383
[10]
[Anonymous], OBS STUD DEV DIAB MA