CuBr2-catalyzed synthesis of bis(indolyl)methanes

被引：149

作者：

Mo, LP ^{[1
]}

Ma, ZC ^{[1
]}

Zhang, ZH ^{[1
]}

机构：

[1] Hebei Normal Univ, Coll Chem, Shijiazhuang 050091, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 15期

基金：

中国国家自然科学基金;

关键词：

aldehydes; bis(indolyl)methanes; copper(II) bromide; indole;

D O I：

10.1081/SCC-200066653

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Copper(II) bromide is found to be an efficient catalyst for the electrophilic substitution reaction of indole with aldehydes to afford the corresponding bis(indolyl)methanes in good yields.

引用

页码：1997 / 2004

页数：8

共 39 条

[1] A convenient method of synthesis of bis-indolylmethanes:: Indium trichloride catalyzed reactions of indole with aldehydes and Schiff's bases. [J].

Babu, G ;

Sridhar, N ;

Perumal, PT .

SYNTHETIC COMMUNICATIONS, 2000, 30 (09) :1609-1614

[2]

Bandgar BP, 2004, MONATSH CHEM, V135, P1265, DOI 10.1007/s00706-004-0206-6

[3]

Bandgar BP, 2004, J CHEM RES, P34

[4] Molecular iodine-catalyzed efficient and highly rapid synthesis of bis(indolyl)methanes under mild conditions [J].

Bandgar, BP ;

Shaikh, KA .

TETRAHEDRON LETTERS, 2003, 44 (09) :1959-1961

[5] VIBRINDOLE-A, A METABOLITE OF THE MARINE BACTERIUM, VIBRIO-PARAHAEMOLYTICUS, ISOLATED FROM THE TOXIC MUCUS OF THE BOXFISH OSTRACION-CUBICUS [J].

BELL, R ;

CARMELI, S ;

SAR, N .

JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1994, 57 (11) :1587-1590

[6]

Chakrabarty M, 2001, HETEROCYCLES, V55, P2431

[7] Dry reaction of indoles with carbonyl compounds on montmorillonite K10 clay: a mild, expedient synthesis of diindolylalkanes and vibrindole A [J].

Chakrabarty, M ;

Ghosh, N ;

Basak, R ;

Harigaya, Y .

TETRAHEDRON LETTERS, 2002, 43 (22) :4075-4078

[8] Lewis acid-catalyzed reactions in protic media. Lanthanide-catalyzed reactions of indoles with aldehydes or ketones [J].

Chen, DP ;

Yu, LB ;

Wang, PG .

TETRAHEDRON LETTERS, 1996, 37 (26) :4467-4470

[9] 6-BROMOTRYPTAMINE DERIVATIVES FROM THE GULF OF CALIFORNIA TUNICATE DIDEMNUM-CANDIDUM [J].

FAHY, E ;

POTTS, BCM ;

FAULKNER, DJ ;

SMITH, K .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (02) :564-569

[10] Ion exchange resin catalyzed condensation of indole and carbonyl compounds -: Synthesis of bis-indolylmethanes [J].

Feng, XL ;

Guan, CJ ;

Zhao, CX .

SYNTHETIC COMMUNICATIONS, 2004, 34 (03) :487-492

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