Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel versus cisplatin and paclitaxel (GOG158) and an update on GOG0182-ICON5

被引:18
作者
Bookman, MA
Greer, BE
Ozols, RF
机构
[1] Fox Chase Canc Ctr, Div Med Sci, Philadelphia, PA 19111 USA
[2] Univ Washington, Sch Med, Div Gynecol Oncol, Seattle, WA USA
关键词
carboplatin; ovarian cancer; paclitaxel; second-look;
D O I
10.1111/j.1525-1438.2003.13362.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Mature results from GOG158 have clearly established carboplatin and paclitaxel as an effective and well-tolerated standard regimen, providing a basis for the reference arm in GOG0182-ICON5, an ongoing multi-armed phase III trial of the Gynecologic Cancer InterGroup (GCIG) evaluating the incorporation of newer cytotoxic agents. Results from GOG158 will be reviewed, including an analysis of second-look surgical outcomes, followed by an update on the current status of GOG0182-ICON5.
引用
收藏
页码:149 / 155
页数:7
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