Versatile and open software for comparing large genomes

被引:3846
作者
Kurtz, S
Phillippy, A
Delcher, AL
Smoot, M
Shumway, M
Antonescu, C
Salzberg, SL
机构
[1] Inst Genom Res, Rockville, MD 20850 USA
[2] Univ Hamburg, Ctr Bioinformat, D-20146 Hamburg, Germany
关键词
D O I
10.1186/gb-2004-5-2-r12
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The newest version of MUMmer easily handles comparisons of large eukaryotic genomes at varying evolutionary distances, as demonstrated by applications to multiple genomes. Two new graphical viewing tools provide alternative ways to analyze genome alignments. The new system is the first version of MUMmer to be released as open-source software. This allows other developers to contribute to the code base and freely redistribute the code. The MUMmer sources are available at http://www.tigr.org/software/mummer.
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页数:9
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