Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part II. Strategies to reduce scar formation after dermatologic procedures

被引：126

作者：

Tziotzios, Christos ^{[1
]}

Profyris, Christos ^{[2
]}

Sterling, Jane ^{[3
]}

机构：

[1] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Cambridge CB2 0QQ, England

[2] Chelsea & Westminster Hosp, Dept Plast & Burns, London, England

[3] Univ Cambridge, Cambridge Univ Hosp NHS Fdn Trust, Dept Dermatol, Cambridge, England

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2012年 / 66卷 / 01期

关键词：

antiscarring agents; cutaneous scar reduction strategies; PULSED-DYE-LASER; FIBROBLAST COLLAGEN-SYNTHESIS; ONION EXTRACT GEL; HYPERTROPHIC SCARS; INTRALESIONAL; 5-FLUOROURACIL; NONABSORBABLE SUTURES; DERMAL FIBROBLASTS; COSMETIC OUTCOMES; STERNOTOMY SCARS; TREATING KELOIDS;

D O I：

10.1016/j.jaad.2011.08.035

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

The evidence base underpinning most traditional scar reduction approaches is limited, but some of the novel strategies are promising and accumulating. We review a number of commonly adopted strategies for scar reduction. The outlined novel agents are paradigmatic of the value of translational medical research and are likely to change the scenery in the much neglected but recently revived field of scar reduction therapeutics. © 2010 by the American Academy of Dermatology, Inc.

引用

页码：13 / 24

页数：12

共 109 条

[1]

Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis [J].