Fusion of mass spectrometry-based metabolomics data

被引：268

作者：

Smilde, AK ^{[1
]}

van der Werf, MJ ^{[1
]}

Bijlsma, S ^{[1
]}

van der Werff-van-der Vat, BJC ^{[1
]}

Jellema, RH ^{[1
]}

机构：

[1] TNO, NL-3700 AJ Zeist, Netherlands

来源：

ANALYTICAL CHEMISTRY | 2005年 / 77卷 / 20期

关键词：

D O I：

10.1021/ac051080y

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A general method is presented for combining mass spectrometry-based metabolomics data. Such data are becoming more and more abundant, and proper tools for fusing these types of data sets are needed. Fusion of metabolomics data leads to a comprehensive view on the metabolome of an organism or biological system. The ideas presented draw upon established techniques in data analysis. Hence, they are also widely applicable to other types of X-omics data provided there is a proper pretreatment of the data. These issues are discussed using a real-life metabolomics data set from a microbial fermentation process.

引用

页码：6729 / 6736

页数：8

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