Phenotypic similarities causing clinical misdiagnosis of pathologically-confirmed sporadic Creutzfeldt-Jakob disease as dementia with Lewy bodies

被引:12
作者
du Plessis, D. G. [2 ]
Larner, A. J. [1 ]
机构
[1] Walton Ctr Neurol & Neurosurg, Cognit Funct Clin, Liverpool L9 7LJ, Merseyside, England
[2] Hope Hosp, Greater Manchester Neurosci Ctr, Salford M6 8HD, Lancs, England
关键词
Creutzfeldt-Jakob disease; dementia with Lewy bodies; diagnosis;
D O I
10.1016/j.clineuro.2007.09.017
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A patient fulfilling central, core and supportive clinical diagnostic criteria for dementia with Lewy bodies deteriorated rapidly in the absence of neuroleptic drug treatment, prompting suspicion of a diagnosis of sporadic Creutzfeldt-Jakob disease. At postmortem examination, the brain showed features typical of Creutzfeldt-Jakob disease of the MV1 subtype. We review the phenotypic overlap between dementia with Lewy bodies and Creutzfeldt-Jakob disease which may cause clinical misdiagnosis. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:194 / 197
页数:4
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