Palladium-catalyzed aminobenzannulation during Sonogashira couplings using o-bromoacetophenone

被引：31

作者：

Herndon, JW ^{[1
]}

Zhang, YS ^{[1
]}

Wang, K ^{[1
]}

机构：

[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2001年 / 634卷 / 01期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

benzannulation; sonogashira coupling; palladium catalysis; alkynylation; cyclization; cycloaddition; o-bromoacetophenone; aminonaphthalenes;

D O I：

10.1016/S0022-328X(01)01104-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The palladium-catalyzed coupling of alkynes with o-bromoacetophenone has been investigated. If this reaction is conducted in an amine solvent and is allowed to proceed for a lengthy reaction time, a benzannulation process, resulting in an aminonaphthalene derivative, follows the expected Sonogashira coupling. The scope and limit of this reaction has been briefly investigated. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：1 / 4

页数：4

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