Remission in Early Rheumatoid Arthritis - A Comparison of New ACR/EULAR Remission Criteria to Established Criteria

被引：34

作者：

Kuriya, Bndee ^{[1
]}

Sun, Ye ^{[1
]}

Boire, Gilles ^{[2
]}

Haraoui, Boulos ^{[3
]}

Hitchon, Carol ^{[4
]}

Pope, Janet E. ^{[5
]}

Thorne, John C. ^{[6
]}

Keystone, Edward C. ^{[1
]}

Bykerk, Vivian P. ^{[1
,7
]}

机构：

[1] Univ Toronto, Mt Sinai Hosp, Div Rheumatol, Toronto, ON M5G 1X5, Canada

[2] Univ Sherbrooke, Div Rheumatol, Sherbrooke, PQ J1K 2R1, Canada

[3] Inst Rhumatol Montreal, Montreal, PQ, Canada

[4] Univ Manitoba, Arthrit Ctr, Winnipeg, MB, Canada

[5] Univ Western Ontario, Div Rheumatol, St Josephs Hlth Care, London, ON, Canada

[6] Southlake Reg Hlth Ctr, Newmarket, ON, Canada

[7] Harvard Univ, Brigham & Womens Hosp, Div Rheumatol, Boston, MA 02115 USA

来源：

JOURNAL OF RHEUMATOLOGY | 2012年 / 39卷 / 06期

关键词：

RHEUMATOID ARTHRITIS; CLINICAL REMISSION; DISEASE ACTIVITY SCORE; RHEUMATOLOGY/EUROPEAN LEAGUE; AMERICAN-COLLEGE; SCORES; RA;

D O I：

10.3899/jrheum.111341

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Objective. To describe the frequency of remission in an early rheumatoid arthritis (ERA) cohort. Methods. The frequency of remission was evaluated, based on 8 definitions including the Boolean-based American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria. Results. Of 369 patients, remission at 12 months ranged from 18% according to the ACR/EULAR clinical trial criteria to 40% according to the 28-joint Disease Activity Score (DAS28) < 2.6. Higher tender joint count, swollen joint count, and physician global scores were seen for DAS28-based definitions, and patient global assessment (PtGA) scores were almost 5-fold higher for DAS28 remission. Conclusion. Remission is achievable in ERA but its frequency differs according to the remission definition applied. Adoption of the new ACR/EULAR definition will limit the number classified as in remission, especially if the PtGA criteria are rated high for reasons other than inflammatory arthritis. (First Release April 15 2012; J Rheumatol 2012;39:1155-8; doi:10.3899/jrheum.111341)

引用

页码：1155 / 1158

页数：4

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